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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC18
All Species:
20.61
Human Site:
S821
Identified Species:
41.21
UniProt:
Q5T9S5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T9S5
NP_996769.2
1454
168962
S821
T
K
L
E
K
Q
V
S
K
L
E
Q
E
L
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537071
1456
169626
S820
T
K
L
E
K
Q
V
S
K
L
E
Q
E
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q640L5
1455
169723
S822
S
K
L
E
K
Q
V
S
K
Q
E
Q
E
L
Q
Rat
Rattus norvegicus
XP_001060717
1462
170487
S825
S
K
L
E
K
Q
V
S
K
Q
E
Q
E
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508531
925
106760
A371
N
E
N
T
E
L
K
A
L
I
A
S
Q
N
E
Chicken
Gallus gallus
XP_001232490
1295
151316
K722
N
E
Q
T
I
K
V
K
Q
L
E
S
A
L
D
Frog
Xenopus laevis
Q9PW73
1335
154049
S770
T
E
L
E
K
Q
V
S
K
L
E
F
E
L
E
Zebra Danio
Brachydanio rerio
XP_692712
779
89837
E225
N
Q
A
L
Q
N
A
E
K
L
T
V
T
F
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
E1156
S
D
L
Q
R
E
L
E
E
L
G
E
K
L
D
Sea Urchin
Strong. purpuratus
XP_796315
2152
245292
S1263
A
Q
L
E
Q
Q
V
S
N
L
S
K
E
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LW85
726
81954
L172
L
K
D
R
E
R
A
L
V
L
K
E
K
D
F
Baker's Yeast
Sacchar. cerevisiae
P25386
1790
206434
Q1014
S
Q
E
K
E
N
F
Q
I
E
R
G
S
I
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.1
N.A.
84.4
83.5
N.A.
41.4
49.3
39.8
22.7
N.A.
N.A.
N.A.
20.2
22.9
Protein Similarity:
100
N.A.
N.A.
95.4
N.A.
92.4
91.4
N.A.
51
65.2
59.5
37.2
N.A.
N.A.
N.A.
40
40
P-Site Identity:
100
N.A.
N.A.
100
N.A.
86.6
86.6
N.A.
0
26.6
80
13.3
N.A.
N.A.
N.A.
20
53.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
93.3
N.A.
40
46.6
93.3
33.3
N.A.
N.A.
N.A.
73.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.7
40.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
17
9
0
0
9
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
0
0
0
0
0
0
0
0
0
9
17
% D
% Glu:
0
25
9
50
25
9
0
17
9
9
50
17
50
0
25
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
9
0
9
9
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
9
9
0
0
0
9
0
% I
% Lys:
0
42
0
9
42
9
9
9
50
0
9
9
17
0
9
% K
% Leu:
9
0
59
9
0
9
9
9
9
67
0
0
0
67
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
25
0
9
0
0
17
0
0
9
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
25
9
9
17
50
0
9
9
17
0
34
9
0
34
% Q
% Arg:
0
0
0
9
9
9
0
0
0
0
9
0
0
0
0
% R
% Ser:
34
0
0
0
0
0
0
50
0
0
9
17
9
0
9
% S
% Thr:
25
0
0
17
0
0
0
0
0
0
9
0
9
0
0
% T
% Val:
0
0
0
0
0
0
59
0
9
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _